Evaluation of easy-to-implement anti-stress interventions in a series of n-of-1 trials: study protocol of the anti-stress intervention among physicians study

HIGHLIGHTS

• What: The authors aim to assess the causal effect of two anti-stress interventions on the level of perceived stress. To calculate the sample size, the approach described by Yang and colleagues was employed, which uses a linear mixed model to estimate sample size in a series of N-of-1 trials. The authors aim to limit deviation from the study protocol due to individual guidance through the study procedure as well as the delivery of the intervention and collection of the daily PRO through a mobile application.
• Who: Uffe Kock Wiil and collaborators from . . .
  

   

  

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