Evaluation of human mesenchymal stromal cells as carriers for the delivery of oncolytic hadv-5 to head and neck squamous cell carcinomas

HIGHLIGHTS

  • who: Robin Nilson and collaborators from the Department of Gene Therapy, University Medical Center Ulm, Ulm, Germany have published the Article: Evaluation of Human Mesenchymal Stromal Cells as Carriers for the Delivery of Oncolytic HAdV-5 to Head and Neck Squamous Cell Carcinomas, in the Journal: Viruses 2023, 218 of /2023/
  • what: This approach showed encouraging results in many preclinical studies and is already being evaluated in the clinic (e_g, NCT03896568, NCT02068794, NCT01844661) . The overall aim of the study was to evaluate the therapeutic potential of hMSCs loaded with replication-competent HAdV-5-HexPos3 vectors . . .

     

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