Evaluation of paired-end sequencing strategies for detection of genome rearrangements in cancer

HIGHLIGHTS

  • who: Ali Bashir and collaborators from the Bioinformatics Graduate Program, University of California San Diego, San Diego, California, United States of America, Comprehensive Cancer Center, University of have published the Article: Evaluation of Paired-End Sequencing Strategies for Detection of Genome Rearrangements in Cancer, in the Journal: (JOURNAL) of April/25,/2008
  • what: The authors further demonstrate how the ability to detect fusion genes depends on the distribution of gene lengths and the authors evaluate how different parameters of a sequencing strategy impact breakpoint detection breakpoint localization and fusion gene detection even in the presence . . .

     

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