Evaluation of pax6 mutant rat as a model for autism

HIGHLIGHTS

  • who: Toshiko Umeda and collaborators from the Division of Developmental Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan, Laboratory for Behavioral and Developmental Disorders have published the Article: Evaluation of Pax6 Mutant Rat as a Model for Autism, in the Journal: (JOURNAL) of December/21,/2010
  • what: The authors further examined behaviors of rSey2/+ rats and revealed that they exhibited abnormality in social interaction (more aggression and withdrawal) in addition to impairment in rearing activity and in fear-conditioned memory. The authors examined whether and/or how much Pax6 heterozygous rats model autism.
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