Evaluation of potential anti-hepatitis a virus 3c protease inhibitors using molecular docking

HIGHLIGHTS

  • who: Reina Sasaki-Tanaka and colleagues from the Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine have published the research: Evaluation of Potential Anti-Hepatitis A Virus 3C Protease Inhibitors Using Molecular Docking, in the Journal: (JOURNAL)
  • what: In vitro studies were introduced to examine the inhibitory effects of HAV subgenomic replicon replication and HAV HA11-1299 genotype IIIA replication in hepatoma cell lines using luciferase assays and real-time RT-PCR. In the present study, compared with the untreated control (100%), Z10325150 monotherapy reduced 47% and 36% of HAV . . .

     

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