HIGHLIGHTS
- who: November et al. from the Midwestern University, United States have published the research work: Evaluation of therapeutic strategies targeting BCAA catabolism using a systems pharmacology model, in the Journal: (JOURNAL)
- what: In this work, a first-in-class QSP model of BCAA catabolism was developed to characterize the dynamic interplay between multiple biological factors (e_g, enzyme activities, concentrations of the co-substrates) and the effect of BT2 inhibition on BCAA concentrations in different compartments. In the current research, the authors report the development and application of the mechanistic mathematical model of BCAA Frontiers in . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.