Evidence for a physical association between the shc-ptb domain and the î²c chain of the granulocyte-macrophage colony-stimulating factor receptor (∗)

HIGHLIGHTS

• who: Joanne C. Pratt from the (UNIVERSITY) have published the article: Evidence for a Physical Association between the Shc-PTB Domain and the βc Chain of the Granulocyte-Macrophage Colony-stimulating Factor Receptor (∗), in the Journal: (JOURNAL)
• how: Taken together these data indicated that the N-terminal PTB domain of Shc is necessary and sufficient for Shc interaction with bc.

SUMMARY

Induction of c-myc and activation of JAK2 require the membrane-proximal 60 amino_acids of the cytoplasmic tail of bc, while a membrane distal domain, between amino_acids 517 and 763 . . .

 



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