Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain

HIGHLIGHTS

• who: Rebecca M. Beiter from the DepartmentUniversity of have published the research: Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain, in the Journal: Scientific Reports Scientific Reports
• what: Using PrimeFlow, a technique that allows for the combination of cellular-resolution RNA detection with the multiplexing capabilities of flow cytometry, the authors demonstrate that a subset of Olig2 expressing cells express Clusterin (OPC1), and a mutually exclusive population expresses Gpr17 (OPC2), with very few OPCs expressing detectable levels of both cluster markers (Fig 7A,B; Supplemental Fig 1). The authors demonstrate that OPCs . . .
  

   

  

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