Evidence of p75 neurotrophin receptor involvement in the central nervous system pathogenesis of classical scrapie in sheep and a transgenic mouse model

HIGHLIGHTS

• who: Tomás Barrio and colleagues from the Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria have published the Article: Evidence of p75 Neurotrophin Receptor Involvement in the Central Nervous System Pathogenesis of Classical Scrapie in Sheep and a Transgenic Mouse Model, in the Journal: (JOURNAL)
• what: The authors investigated the distribution of several neurotrophins and their receptors including p75NTR in the brain of naturally scrapieaffected sheep and experimentally infected ovinized transgenic mice and its correlation with other markers of prion disease. Given the apparent labeling of astrocytes by the anti-p75NTR . . .
  

   

  

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