Evidence that zika virus is transmitted by breastfeeding to newborn a129 (ifnar1 knock-out) mice and is able to infect and cross a tight monolayer of human intestinal epithelial cells

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  • who: Pierre-Emmanuel Ceccaldi and Aurore Vidy from the Federal University of Minas Gerais, Brazil have published the article: Evidence That Zika Virus Is Transmitted by Breastfeeding to Newborn A129 (Ifnar1 Knock-Out) Mice and Is Able to Infect and Cross a Tight Monolayer of Human Intestinal Epithelial Cells, in the Journal: (JOURNAL)
  • what: Tightness validation of the model was also completed with morphological integrity study of Caco-2/TC7 monolayers (visualization of tight junctions and brush border) by transmission electron microscopy, as previously described (Monel et_al, 2017). The authors demonstrate that the different clones . . .

     

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