Evolution of 3d cultures: toward tailored preclinical models

HIGHLIGHTS

  • who: Roberto Benelli and collaborators from the SSD Oncologia Molecolare e Angiogenesi, IRCCS Ospedale Policlinico San Martino, Genova, Italy have published the article: Evolution of 3D Cultures: Toward Tailored Preclinical Models, in the Journal: Cancers 2023, 15, 515. of /2023/
  • what: It is now widely recognized that the TME, especially the ECM composition and structure, is strictly entwined with tumor fate; nevertheless, neither animal nor 3D in_vitro models have, thus far, fulfilled all the requirements for reliable, reproducible and unexpensive preclinical settings.
  • future: Certainly these drawbacks will be overcome in the next future . . .

     

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