Evolution of giant pandoravirus revealed by crispr/cas9

HIGHLIGHTS

• who: Hugo Bisio from the (UNIVERSITY) have published the article: Evolution of giant pandoravirus revealed by CRISPR/Cas9, in the Journal: (JOURNAL) of 16/08/2022
• what: The authors demonstrate the existence of an essential core region in pandoravirus, which corresponds with the accumulation of evolutionary conserved genes across their proposed smaller viral ancestors. The authors demonstrate the essentiality of the icosahedral Major Capsid Protein in mollivirus, a phylogenetically related virus and previously proposed Nature Communications | 14:428 To achieve genetic manipulation of GVs, the authors built an Acanthamoeba castellani CRISPR/Cas9 system, using a . . .
  

   

  

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