HIGHLIGHTS
- who: Ornella Affinito from the IRCCS Synlab SDN SPA, Via Gianturco, Naples, Italy have published the Article: Evolution of intra-tumoral heterogeneity across different pathological stages in papillary thyroid carcinoma, in the Journal: (JOURNAL)
- what: On the other side, as regards the intra-tumoral heterogeneity, most studies focused on the most prevalent genetic alterations in PTC, the BRAF V600E mutation and RET rearrangements . The authors analyzed the whole-exome sequencing data from The analysis showed that stages 3 and 4 were significantly associated with a poor prognosis (p-value=0.0073 and p-value=1 . . .
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