Evolution of substrate specificity within a diverse family of β/α-barrel-fold basic amino acid decarboxylases

HIGHLIGHTS

• who: Xiaoyi Deng from the is not found in single-membrane bacteria (Firmicutes and Actinobacteria) or archaea (5)An important aspect of the evolution of ADC was the four-helical bundle interdomain insertion, raising the possibility of an ancestral form of ADC lacking the insertion. Within bacteria and archaea, ODC is found mainly in the ␣-proteobacteria, which suggests that the eukaryotic ODC may have originated from the ␣-proteobacterial ancestor of the mitochondrion. Gene duplication not only led to diversification of polyamine biosynthesis, from, Arg and, Orn by ADC and ODC but also led to elongation of the . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.