Evolutionarily conserved regulators of tau identify targets for new therapies

HIGHLIGHTS

• who: Jiyoen Kim from the Department of Medicine, Houston, TX, USA have published the research: Evolutionarily conserved regulators of tau identify targets for new therapies, in the Journal: (JOURNAL) of March/15,/2023
• what: The authors used a cross-species screening strategy to examine 6,600 potentially druggable genes in both human cells and fruit flies. Given the invasive nature of ASO therapies and the need to treat individuals at risk for decades, the study focused on discovering potentially druggable gene products that can regulate tau levels.
• how: The authors identified and validated . . .
  

   

  

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