Evolutionary and cellular analysis of the ‘ dark ’ pseudokinase pskh2

HIGHLIGHTS

  • who: Dominic P. Byrne and collaborators from the Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool , ZB, UK. have published the paper: Evolutionary and cellular analysis of the u2018 dark u2019 pseudokinase PSKH2, in the Journal: (JOURNAL) of 23/01/2023
  • what: As the authors show below, N-terminal modification(s) are important for PSKH2 subcellular distribution, conceptually similar to findings with PSKH1 and its targeting to the Golgi apparatus . The authors demonstrate that full-length vertebrate PSKH2 fully justifies its pseudokinase moniker , since PSKH2 protein . . .

     

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