Evolutionary loss of inflammasomes in the carnivora and implications for the carriage of zoonotic infections

HIGHLIGHTS

• who: Zsofia Digby from the University of Veterinary Medicine, Cambridge CB ES, UK have published the research work: Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections, in the Journal: (JOURNAL) of August/24,/2021
• what: The authors show that key inflammasome lytic cell death pathways thought to be critical for gut health in mammals are either genetically and/or functionally missing from the Carnivora.
• how: To characterize inflammasome functionality in Carnivora the authors compared the kinetics and magnitude of cell death between immortalized bone marrow-derived . . .
  

   

  

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