Evolving polarisation of infiltrating and alveolar macrophages in the lung during metastatic progression of melanoma suggests ccr1 as a therapeutic target

HIGHLIGHTS

• who: Thomas T. Tapmeier from the Animal studies Female, week old C BL/, mice were obtained from Charles River UK, Ltd(Margate, UK), housed in IVC units, and given food and water ad libitum. Animals were treated in accordance with the Animals (Scientific Procedures) Act , and the University of Oxford ethical guidelines. Mice were s.c. injected with , u00d7 , B , cells in , u03bcl sterile PBS under general anaesthesia with Isoflurane. Tumour growth was monitored and the tumour size measured with a caliper twice per week. The tumour volume was calculated according to the formula V=u03c0/, u00d7 . . .
  

   

  

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