Ex vivo feedback control of neurotransmission using a photocaged adenosine a1 receptor agonist

HIGHLIGHTS

• who: Erine Craey et al. from the Brain, Department of Head and Skin, Ghent University, Ghent, Belgium have published the article: Ex Vivo Feedback Control of Neurotransmission Using a Photocaged Adenosine A1 Receptor Agonist, in the Journal: (JOURNAL)
• what: The authors report the design synthesis and validation of the novel compound N6 -cyclopentyladenosine (cCPA) to achieve precisely localized and timed release of the parent CPA using 405 nm light. The authors explore the photopharmacological approach known as photocaging in which a bioactive ligand is typically linked to a photocleavable group that renders the ligand inactive . . .
  

   

  

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