Examination of the tigit-cd226-cd112-cd155 immune checkpoint network during a healthy pregnancy

HIGHLIGHTS

  • who: Matyas Meggyes and colleagues from the Department of Medical Microbiology and Immunology, Medical School, University of, Szigeti Street, Halle, Germany have published the research work: Examination of the TIGIT-CD226-CD112-CD155 Immune Checkpoint Network during a Healthy Pregnancy, in the Journal: (JOURNAL)

SUMMARY

    After MHC-TCR ligation, stimulatory receptors (CD40, OX-40, CD27, CD137, ICOS) mediate co-stimulatory signals that provide T_cell cytotoxicity and proliferation. TIGIT is expressed by several immune cell subpopulations, including ing NK and NKT, memory and activated T_cells, follicular T helper and regulatory NK and NKT, memory . . .

     

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