Examining the role of paraoxonase 2 in the dopaminergic system of the mouse brain

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  • who: Jacqueline M. Garrick from the Wild-type (WT) and , deficient (PON2-def ) mice [10] on a C BL/, J background were used for this studyN=, mice per sex per genotype were utilized, with male and female mice combined for analysis if no sex difference was observed. Mice were euthanized at postnatal day (PND) , using carbon dioxide (u00adCO2) followed by decapitation. Striatal tissue was dissected and flash frozen in liquid nitrogen. Tissue was pulverized with a pre-chilled mortar and pestle into a fine powder, stored at, u00b0C and aliquoted into appropriate lysis buffers for protein and . . .

     

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