HIGHLIGHTS
- who: Xuanye Cao from the (UNIVERSITY) have published the Article: Excess folic acid intake increases DNA de novo point mutations, in the Journal: (JOURNAL)
- how: This result is consistent with studies on folate status and related congenital malformations including NTDs1 and CHDs2.
- future: The genome and epigenome impairment induced by either high FA or low FA diets should be further confirmed in human population in future studies. Studies are required to test the link between hypermethylation and gene_expression at different time points.
SUMMARY
DNA was obtained from 77 mouse . . .
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