HIGHLIGHTS
- What: The authors report here using transmission electron microscopy (TEM) that glioma cells produce an excessive amount of lipids that are found broadly in many cellular structures and tumor microenvironment, including the cytoplasm, mitochondrial_matrix, and nucleus of tumor cells, as well as spread to tumor vessel walls and lumina. The authors examine lysosome prevalence, glycogen droplets, plasma_membrane integrity, and chromatin structure. This approach has been employed in breast cancer, wherein it was shown that inhibition of fatty_acid synthesis inhibited cancer cell growth in brain metastase . The ultrastructural analysis presented in this study provides valuable insights into lipid . . .
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