Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis

HIGHLIGHTS

• who: Bartosz Wiernicki from the Casp11-/- mice were generated by sequentially breeding parental Casp4tm1b(KOMP)Wtsi mice (KOMP ID CSD47499) with Flp-deleter mice to remove the Frt site flanked LacZ reporter and Neomycin selection cassette, and with Cre-deleter mice to remove LoxP site flanked exons , and Gsdmd-/- mice and GsdmdI N mutant (C BL/ Janu-Gsdmdm Anu/AnuApb) mice were kindly provided by Dr. Vishva M. Dixit (Genentech) and the Australian Phenomics Facility at the Australian National University, respectively12. All mice were bred in specific pathogen-free animal facilities and were females between have published . . .
  

   

  

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