Excitatory/inhibitory imbalance in autism: the role of glutamate and gaba gene-sets in symptoms and cortical brain structure

HIGHLIGHTS

• who: Viola Hollestein from the Participants We included participants from the Longitudinal European Autism Project (LEAP), part of the AIMS-2-TRIALS clinical research programme (https:// wwwaims-2-trials.eu/) [38-40]. Our sample consisted of , participants (n=, autistic and n=, neurotypical controls) for whom structural MRI data was available that passed quality control [19]. Phenotypic, genetic and brain imaging data were collected at six study centers across Europe: Institute of Psychiatry, Psychology and Neuroscience, King`s College London (IoPPN/KCL, UK), Autism Research Centre, University of Cambridge (UCAM, UK), University Medical Centre Utrecht (UMCU, Netherlands), Radboud . . .
  

   

  

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