HIGHLIGHTS
SUMMARY
CD8+ T_cells contribute to atherogenesis by secretion of cytotoxic granules and the formation of the necrotic core of atherosclerotic plaques19. CD4+ T_cells and B cells have also been previously implicated in CVD21-31. The authors present a novel method (‘attractor analysis`) that uses the models learned by scBONITA to identify pathwaynpj Systems Biology and Applications 35 specific signaling states for CD8+ T_cells and monocytes. A population of CD8 T_cells/NK resting cells were lower in ASPLWH and a population of CD14+ CD16+ monocytes were higher in AS- PLWH (t-test, p and amp;lt . . .
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