Exendin-4 alleviates β-amyloid peptide toxicity via daf-16 in a caenorhabditis elegans model of alzheimer’s disease

HIGHLIGHTS

  • who: Xiangwei Song and Xueli Wang from the Heidelberg University, Germany have published the research: Exendin-4 alleviates β-Amyloid peptide toxicity via DAF-16 in a Caenorhabditis elegans model of Alzheimer's disease, in the Journal: (JOURNAL)
  • what: The authors focused on the area near the pharynx of C. elegans CL4176 to count the number of deposits. The authors investigated the neuroprotective effects of Exendin-4 in C. elegans model of AD for the first time.
  • how: The onset of paralysis was prolonged in CL4176 and CL2006 worms in a dose-dependent manner . . .

     

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