Exogenous mg-atp induces a large inhibition of pyruvate kinase in intact rat hepatocytes*

HIGHLIGHTS

  • who: Carole Ichai from the (UNIVERSITY) have published the paper: Exogenous Mg-ATP Induces a Large Inhibition of Pyruvate Kinase in Intact Rat Hepatocytes*, in the Journal: (JOURNAL) of May/16,/2000
  • what: The authors studied the effects of exogenous Mg-ATP in rat liver cells perifused with dihydroxyacetone to investigate simultaneously gluconeogenetic and glycolytic pathways.

SUMMARY

    The main effect on gluconeogenesis was located at the level of the fructose cycle, whereas the decrease in glycolysis was due to a strong inhibition of pyruvate kinase. Although pyruvate kinase inhibition induced by . . .

     

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