Exosomal ap000439.2 from clear cell renal cell carcinoma induces m2 macrophage polarization to promote tumor progression through activation of stat3

HIGHLIGHTS

• who: Tianyi Shen from the Department of Urology, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, Jiangsu, China have published the research: Exosomal AP000439.2 from clear cell renal cell carcinoma induces M2 macrophage polarization to promote tumor progression through activation of STAT3, in the Journal: (JOURNAL)
• what: The authors investigated the effect of ccRCC-derived exosomes on TAMs and identified the key exosomal lncRNA in this process. The study provide novel insight into the polarization mechanism of macrophage induced by ccRCC and a promising therapeutic target treatment. The authors examine whether . . .
  

   

  

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