Exosomal ctcf confers cisplatin resistance in osteosarcoma by promoting autophagy via the igf2-as/mir-579-3p/msh6 axis

HIGHLIGHTS

  • who: Haibo Zhan and colleagues from the Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China have published the research work: Exosomal CTCF Confers Cisplatin Resistance in Osteosarcoma by Promoting Autophagy via the IGF2-AS/miR-579-3p/MSH6 Axis, in the Journal: Journal of Oncology of 31/05/2022
  • what: The authors aim to investigate the role of cisplatin(CDDP-) resistant osteosarcoma- (OS-) derived exosomal CTCF in OS cell resistance to CDDP and its mechanistic basis. The focus of this study shifted to find the downstream genes of IGF2-AS . . .

     

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