Exosomal lncrnas from mesenchymal stem cells as the novel modulators to cardiovascular disease

HIGHLIGHTS

  • who: Ying Huang from the (UNIVERSITY) have published the paper: Exosomal lncRNAs from mesenchymal stem cells as the novel modulators to cardiovascular disease, in the Journal: (JOURNAL)
  • future: Study is needed to fully understand the characteristics of exosomal lncRNAs.

SUMMARY

    Prepared from macrophage migration inhibitory factor (MIF)-induced MSCs blocked H2O2-induced apoptosis in cardiomyocytes by modulating the expression of miR-1423p and activating Forkhead class O1 (FOXO1). Similar to lncRNA-NEAT1, other MSC-derived exosomal lncRNAs showed activity in CVD. Exosomal metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), derived from . . .

     

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