Exosomal mir-146a-5p and mir-155-5p promote cxcl12/cxcr7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts

HIGHLIGHTS

• who: Dong Wang from the Clinical specimens Human CRC tissue specimens and adjacent normal mucosa were obtained from CRC patients who underwent surgery in Xuanwu Hospital of Capital Medical University (Beijing, China) and were confirmed by pathological analysis (n=24)The clinicopathological features are shown in Table, . The tissues were stored in RNAlater solution (Qiagen, USA) at , u00b0C. Human serum samples were collected from CRC patients (n=17) including metastatic (n=7) and non-metastatic (n=10) CRC patients, as well as healthy donors (n=13). The blood samples were centrifuged at, g for , min to extract . . .
  

   

  

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