HIGHLIGHTS
- who: Natascha Fussi from the (UNIVERSITY) have published the research: Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy, in the Journal: (JOURNAL)
- what: The authors aimed to investigate the effects of autophagy inhibition on α-Syn-induced cell death.
- how: As marker for autophagosomes the authors used Western blotting for LC3B-II which is generated from LC3B-I by phosphatidylethanolamine conjugation22-24.
SUMMARY
The authors overexpressed α-Syn by adenoviral transduction and silenced ATG5 by siRNA transfection. α-Syn overexpression, a control siRNA against GAPDH, and overexpression of . . .
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