Expanding the toolbox of metabolically stable lipid prodrug strategies

HIGHLIGHTS

• who: HIV et al. from the Yat-sen University, China have published the research: Expanding the toolbox of metabolically stable lipid prodrug strategies, in the Journal: (JOURNAL)
• what: To test this hypothesis, the authors aimed to synthesize and evaluate TXL analogues featuring additional oxygen atoms spaced 5 methylene units apart, as well as a small series of polyethylene glycol (PEG)-type derivatives.
• future: Comparison of the metabolic stability of matched molecular pairs containing lipid prodrug motifs of 19 20 and 21 atoms will be the subject of future investigation. Future experiments will involve . . .
  

   

  

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