Expansion of the catalytic repertoire of alcohol dehydrogenases in plant metabolism**

HIGHLIGHTS

  • who: Angewandte et al. from the (UNIVERSITY) have published the article: Expansion of the Catalytic Repertoire of Alcohol Dehydrogenases in Plant Metabolism**, in the Journal: (JOURNAL)
  • what: The authors report the crystal_structure of dihydroprecondylocarpine acetate synthase (DPAS), an ADH that catalyses the non-canonical 1,4reduction of an u03b1,u03b2-unsaturated iminium moiety. The authors report four crystal_structures of apo- and substratebound DPAS from two phylogenetically related species. The authors show the structural basis of how ADHs can catalyse two distinct variations on carbonyl reduction.
  • how: To establish a point of comparison for . . .

     

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