Experimental autoimmune encephalomyelitis of mice: enzymatic cross site-specific hydrolysis of h4 histone by iggs against histones and myelin basic protein

HIGHLIGHTS

  • who: Andrey E. Urusov et al. from the Institute of Chemical Biology and Fundamental Medicine of the Siberian Division of Russian Academy have published the research: Experimental Autoimmune Encephalomyelitis of Mice: Enzymatic Cross Site-Specific Hydrolysis of H4 Histone by IgGs against Histones and Myelin Basic Protein, in the Journal: (JOURNAL) of 11/08/2022
  • what: In this work, for the first time, using the example of abzymes hydrolyzing histone H4, an analysis of the hydrolysis sites of this histone was carried out depending on the antigen (MOG or DNA-histone complex) and the stage . . .

     

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