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- who: Jean-François Timsit from the The Institute for Healthcare Improvement recommends a five-step programme for the prevention of CRI: hand hygiene, maximal barrier precautions upon insertion, chlorhexidine skin antisepsis, optimal catheter site selection, and daily review of line necessity, with prompt removal of unnecessary linesAlthough the individual value of these measures appears to be less obvious in children, the existence of a quality improvement programme combining these measures allows a reduction of the incidence density (ID) of CRI in paediatric intensive care units. In the meta-analysis performed by Ista et_al the ID in . . .

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