HIGHLIGHTS
- who: Marcus J. G. W. Ladds from the (UNIVERSITY) have published the paper: Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology, in the Journal: (JOURNAL) of August/18,/2020
- what: This study shows the complex mechanisms that govern the manner in which molecules differ in their abilities to target a particular protein even when the differences between molecules are localized in their seemingly noninteracting regions. And in agreement with the previous study that demonstrates that DHODH is a remarkably frequent target , the authors show that certain tenovins . . .
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