Exploration and validation of metastasis-associated genes for skin cutaneous melanoma

HIGHLIGHTS

• who: Hong Luan from the Department of Laboratory China Medical University have published the article: Exploration and validation of metastasis-associated genes for skin cutaneous melanoma, in the Journal: Scientific Reports Scientific Reports
• what: 294 DEGs between the primary and metastatic skin cutaneous melanoma samples were screened, and four hub genes, CDK1, FOXM1, KIF11, and RFC4, were identified that may be associated with the metastasis of melanoma.
• how: The results showed that three hub genes (CDK1 KIF11 and RFC4) were significantly upregulated in metastatic melanoma tissues compared in primary melanoma tissues (Fig 4a . . .
  

   

  

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