HIGHLIGHTS
- who: Sarah Tessier from the (UNIVERSITY) have published the research work: Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells, in the Journal: (JOURNAL) of 29/09/2022
- what: The authors demonstrate that PML is essential for oxidative stress-driven partner SUMO2/3 conjugation in mouse ESCs (mESCs) or leukemia, a process often followed by their poly-ubiquitination and degradation. All the experiments were performed on an EASY-nLC 1000 system (Proxeon, Odense, Denmark) connected to a Q-Exactive Orbitrap (Thermo Fisher Scientific, Germany) through a nano . . .
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