Exploration of the potential mechanism of the common differentially expressed genes in psoriasis and atopic dermatitis

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SUMMARY

    Psoriasis is a chronic inflammatory disease characterized by periodic continuous inflammation and relief, uncontrolled proliferation of keratinocytes, and impaired differentiation of keratinocytes. The authors analyzed the gene_expression pattern by reanalyzing the data of GSE14905 (psoriasis) and GSE32924 (atopic dermatitis) deposited in Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were identified, and gene function enrichment analysis was performed for psoriasis and atopic dermatitis, respectively. Two sets of databases, GSE14905 (psoriasis) and GSE32924 (atopic dermatitis), were obtained from gene_expression omnibus (GEO, http:// www.ncbi.nlm.nih.gov/geo/). GSE32924 contains 25 expression data sets . . .

     

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