HIGHLIGHTS
- who: Ishita N. Waghela and collaborators from the The University of Newcastle, Australia have published the paper: Exploring in vitro expression and immune potency in mice using mRNA encoding the Plasmodium falciparum malaria antigen, CelTOS, in the Journal: (JOURNAL)
- what: An experiment was conducted to examine if a second boost of pfceltos encoding mRNA-LNP improved immunogenicity to CelTOS. In the present study, mRNA-LNP encoding pfceltos with varying signal sequences, N-glycosylation, nucleoside substitutions along with LNP (LNP1 versus LNP3) and coding/noncoding regions of mRNA (TriLink versus UPenn) were explored to identify an . . .
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