Exploring novel fluorine-rich fuberidazole derivatives as hypoxic cancer inhibitors: design, synthesis, pharmacokinetics, molecular docking, and dft evaluations

HIGHLIGHTS

• who: Muhammad Babar Taj et al. from the Studies University, CHINA have published the article: Exploring novel fluorine-rich fuberidazole derivatives as hypoxic cancer inhibitors: Design, synthesis, pharmacokinetics, molecular docking, and DFT evaluations, in the Journal: PLOS ONE of 28/07/2022
• what: Because of these facts, the authors intended to synthesize some novel fuberidazole derivatives as potential targets for DNA ruin at hypoxia MCF-7 cells. NBO analysis is carried out to investigate the donor-acceptor interaction.
• how: The results indicated that the synthesized compounds (5a 5c-5e 5g-5I and 5m . . .
  

   

  

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