Exploring selective autophagy events in multiple biologic models using lc3-interacting regions (lir)-based molecular traps

HIGHLIGHTS

• who: Gru00e9goire Quinet from the Laboratoire have published the Article: Exploring selective autophagy events in multiple biologic models using LC3-interacting regions (LIR)-based molecular traps, in the Journal: Scientific Reports Scientific Reports of 14/07/2021
• what: The authors could show for the first time, involvement of LC3 proteins rather than GABARAP proteins in the recognition of proteasome in proteaphagy.
• how: The results indicated that LC3-traps containing 2 LIRs show different preferences for distinct LC3/GABARAP family members (Fig 3A) while LC3-trap Wx2 preferentially interacts with LC3A and LC3B proteins . . .
  

   

  

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