Exploring the action mechanism of the active ingredient of quercetin in ligustrum lucidum on the mouse mastitis model based on network pharmacology and molecular biology validation

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SUMMARY

    In the three stage model group, it was obvious that the glandular follicle structure was severely damaged, the glandular lumen was filled with shed epithelial_cells, and there were a large number of lymphocytes as well as bruises in the glandular interstitial space. To acting as a bactericide, it also inhibited LPS, Escherichia coli, and Staphylococcus aureus-induced apoptosis of mammary epithelial_cells in cows.In addition, the core targets obtained were TNF, IL6, and AKT1. From the pathological histological point of view, it was observed that the mammary epithelial_cells in the blank control mice were . . .

     

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