Exploring the genetic basis of human population differences in dna methylation and their causal impact on immune gene regulation

HIGHLIGHTS

• who: Lucas T. Husquin from the The EvoImmunoPop collection consists of , individuals (males between , and , years old, mean , years old) from two different ancestries (, of European and , of African descent), who were recruited at the Center for Vaccinology from the Ghent University Hospital (Ghent, Belgium) [48]. For each participant, ml of whole blood was collected into anticoagulant EDTA-blood collection tubes and peripheral blood mononuclear cells (PBMCs) were purified using Ficoll-paque density gradients (#17-1440-03, GE Healthcare). Monocytes were positively selected from purified PBMCs using magnetic , microbeads (#130-050-201, MiltenyiBiotec), as per manufacturer's . . .
  

   

  

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