Exploring the impact of trem2 in tumor-associated macrophages

HIGHLIGHTS

  • who: Darya Khantakova and colleagues from the Department of Pathology and Immunology, Washington University School of Medicine have published the article: Exploring the Impact of TREM2 in Tumor-Associated Macrophages, in the Journal: Vaccines 2022, 10, 943. of /2022/
  • how: The authors showed that TREM2 was mainly expressed in TAMs in sections from patients and in the MCA1956 murine model .
  • future: Future studies will be needed to further elucidate the functional relevance of TAM heterogeneity in_vivo and help develop TAM-targeting treatments in different tumors. Studies are needed to elucidate several aspects of . . .

     

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