Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (marvel study)

HIGHLIGHTS

  • who: Célia Lloret-Linares from the Inserm, , Paris, France have published the article: Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study), in the Journal: (JOURNAL)
  • what: The aim of this project is to explore the relationship between the activity of drug-metabolizing enzymes (DME) assessed by a phenotypic approach and the concentrations of Venlafaxine (VLX) + O-demethyl-venlafaxine (ODV) the efficacy and tolerance of VLX. major depressive episode MADRS over or equal to treatment with VLX regardless of the dose during at least weeks.

SUMMARY . . .

 

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