HIGHLIGHTS
SUMMARY
The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a chloride (Cl-) and bicarbonate (HCO-3) channel expressed at the apical plasma_membrane (PM) of epithelial_cells in a wide variety of tissues. During EMT epithelial_cells lose, to variable degrees, their specialized features, including strong cell-cell junctions, apicalbasal polarity, cell shape, and cytoskeleton organization. Depending on the biological context, epithelial_cells undergoing EMT can co-express epithelial and mesenchymal phenotypes, that is, partial EMT. The aim here is to elucidate how CFTR, an apical anion_channel, can impact such a broad process that can completely change the . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.