Exposure misclassification bias in the estimation of vaccine effectiveness

HIGHLIGHTS

  • who: Ulrike Baum and collaborators from the University of Helsinki, Helsinki, Finland, Department of and have published the research: Exposure misclassification bias in the estimation of vaccine effectiveness, in the Journal: PLOS ONE of April/15,/2020
  • what: The authors show how the estimation of vaccine effectiveness can be adjusted for exposure misclassification if the sensitivity and specificity of exposure measurement are known or estimable from external sources. The exposure misclassification model (Fig 1) is a special case of the model presented by Tang et_al for misclassification in both exposure and outcome.
  • how . . .

     

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